Determination of Toxic and Anthelmintic Activities of Ornithogalum nutans L., Sternbergia lutea (L.) Ker-Gawl. ex Spreng. and Allium stylosum O.Schwarz

Authors

  • Mehmet Özgür Atay Department of Moleculer Biology and Genetics, Faculty of Science, Muğla Sıtkı Koçman University, Muğla, Turkey
  • Buse Ardıl Department of Moleculer Biology and Genetics, Faculty of Science, Muğla Sıtkı Koçman University, Muğla, Turkey
  • Mehlika Alper Department of Moleculer Biology and Genetics, Faculty of Science, Muğla Sıtkı Koçman University, Muğla, Turkey
  • Olcay Ceylan Department of Biology Faculty of Science, Muğla Sıtkı Koçman University, Muğla, Turkey

Keywords:

Ornithogalum nutans, Sternbergia lutea, Allium stylosum, Artemia salina, Anthelmintic activity

Abstract

In this study, toxic and anthelmintic activities of methanol extracts of aerial and underground parts of Ornithogalum nutans L., Sternbergia lutea (L.) Ker-Gawl. ex Spreng. and Allium stylosum O.Schwarz were investigated. In order to determine the anthelmintic activity, the time elapsed for the duration of paralysis and death was determined after the extracts of different concentrations (10, 20 and 30 mg/mL) were added to the Tubifex tubifex in petri dishes. Each concentration of A. stylosum aerial and underground parts extracts showed high anthelmintic activity. In addition, aerial extract of O. nutans at a concentration of 30 mg/mL showed high anthelmintic activity. A. stylosum extracts showed a higher activity than the standard anthelmintic drug. The toxic activity was determined against Artemia salina with brine shrimp lethality test. Among all extracts, the underground extract of S. lutea showed the highest activity with 0.002 mg/mL, LC50, the aerial extract of O. nutans showed the lowest activity with 0.03 mg/mL, LC50. Aerial and underground methanol extracts of A. stylosum showed high anthelmintic and lethal activity, but more specific studies are needed.

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Published

2021-06-15

How to Cite

Atay, M. Özgür, Ardıl, B., Alper, M., & Ceylan, O. (2021). Determination of Toxic and Anthelmintic Activities of Ornithogalum nutans L., Sternbergia lutea (L.) Ker-Gawl. ex Spreng. and Allium stylosum O.Schwarz. Natural Products and Biotechnology, 1(1), 38–48. Retrieved from https://natprobiotech.com/index.php/natprobiotech/article/view/13

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