Phenolic Compounds Screening and Potential of Larvicidal Activity of Water Extract of Cyclamen cilicium Boiss. & Heldr.


  • Murat Turan Department of Molecular Biology and Genetics, Faculty of Science, Erzurum Technical University, Erzurum, Turkey
  • Ramazan Mammadov Department of Molecular Biology and Genetics, Faculty of Science, Muğla Sıtkı Koçman University, Muğla, Turkey


Cyclamen cilicium, Musca domestica, Culex pipiens, HPLC


This study was designed to phenolic compound analysis with UPLC-ESI-MS/MS, larvicidal (against Musca domestica and Culex pipiens) activities with fresh and underground parts of water extract of Cyclamen cilicium Boiss. & Heldr. Thirty one standard phenolic compounds were used in UPLC-ESI-MS/MS analysis, and ferulic acid was found to value 4483.34 mg/kg as the major compound. The fresh part was found a potential larvicidal activity with 33.33 ± 4.81 % against M. domestica and the fresh part was found potential larvicidal activity than underground part with 0.43 ± 0.09 mg/mL, LC50 against Cx. pipiens. These results about C. cilicium were shown as a potential biolarvicidal potential and can be used in the pharmaceutical, agricultural industry.


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How to Cite

Turan, M., & Mammadov, R. (2021). Phenolic Compounds Screening and Potential of Larvicidal Activity of Water Extract of Cyclamen cilicium Boiss. & Heldr . Natural Products and Biotechnology, 1(1), 1–8. Retrieved from



Research Article